Even though the pharma pack posted a strong rally on Friday, equity benchmarks ended lower as the banking and financial stocks weighed down the market.
The Sensex closed the session 134 points down at 38,845 and the Nifty ended trading at 11,504, falling 0.10%.
HDFC Bank, Shree Cements, Bajaj Finserv, Kotak Mahindra Bank and Maruti were the top five index losers. On the other hand, Dr Reddy, Cipla, Adani Ports, Bharti Airtel and M&M were the top gainers.
While the Bank Nifty closed 1.30% in the red, the Nifty Pharma index gained 5%.
The rupee strengthened by 21 paise to close at 73.45 against the US dollar.