Though his status as a Mutant was never officially confirmed, Olivier Richters' Ursa Major was chronologically the first Mutant to appear in the MCU.
Kamala Khan was confirmed to be a Mutant in the finale of her Disney+ show. Though she was originally an Inhuman in the comics, the MCU retconned this
The philandering and unkillable "Homo supremus" made an appearance in "She-Hulk: Attorney At Law", portrayed by David Pasquesi.
A Variant of Charles Xavier, played yet again by Sir Patrick Stewart, appeared in the "Doctor Strange" sequel, only to be killed by the Scarlet Witch
Portrayed by Tenoch Huerta, Namor the Submariner was the first Mutant in the MCU, name-dropped as such on the big screen.
A Variant of Hank McCoy was played by Kelsey Grammer in the post-credits scene for "The Marvels", reprising his role from the Fox X-Men franchise.
An honorary member of the X-Men in the comics, a Maria Rambeau Binary Variant, played by Lashanna Lynch, appeared alongside Kelsey Grammer's Beast.